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DeCS
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Descriptor English:
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Receptors, Leukocyte-Adhesion
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Descriptor Spanish:
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Receptores de Adhesión de Leucocito
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Descriptor Portuguese:
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Receptores de Adesão de Leucócito
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Synonyms English:
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Family, Leu-CAM Receptor
Leu CAM Receptor Family
Leu-CAM Receptor Family
Leukocyte Adhesion Receptor
Leukocyte Adhesion Receptor Family
Leukocyte Adhesion Receptors
Leukocyte-Adhesion Receptor
Leukocyte-Adhesion Receptor Family
Leukocyte-Adhesion Receptors
Receptor Family, Leu-CAM
Receptor, Leukocyte-Adhesion
Receptors, Leukocyte Adhesion
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Tree Number:
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D12.776.543.750.705.408.600
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Definition English:
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Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells. |
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See Related English:
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Leukocyte-Adhesion Deficiency Syndrome
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History Note English:
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90
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Allowable Qualifiers English:
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Record Number:
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24855
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Unique Identifier:
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D016028
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Occurrence in VHL:
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Similar:
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DeCS
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